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Essential Oil Extraction, Chemical Analysis and Anti-Candida Activity of Calamintha nepeta (L.) Savi subsp. glandulosa (Req.) Ball—New Approaches

A comprehensive study on essential oils extracted from different Calamintha nepeta (L.) Savi subsp. glandulosa (Req.) Ball samples from Tarquinia (Italy) is reported. In this study, the 24-h steam distillation procedure for essential oil preparation, in terms of different harvesting and extraction t...

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Autores principales: Božović, Mijat, Garzoli, Stefania, Sabatino, Manuela, Pepi, Federico, Baldisserotto, Anna, Andreotti, Elisa, Romagnoli, Carlo, Mai, Antonello, Manfredini, Stefano, Ragno, Rino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155801/
https://www.ncbi.nlm.nih.gov/pubmed/28134788
http://dx.doi.org/10.3390/molecules22020203
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author Božović, Mijat
Garzoli, Stefania
Sabatino, Manuela
Pepi, Federico
Baldisserotto, Anna
Andreotti, Elisa
Romagnoli, Carlo
Mai, Antonello
Manfredini, Stefano
Ragno, Rino
author_facet Božović, Mijat
Garzoli, Stefania
Sabatino, Manuela
Pepi, Federico
Baldisserotto, Anna
Andreotti, Elisa
Romagnoli, Carlo
Mai, Antonello
Manfredini, Stefano
Ragno, Rino
author_sort Božović, Mijat
collection PubMed
description A comprehensive study on essential oils extracted from different Calamintha nepeta (L.) Savi subsp. glandulosa (Req.) Ball samples from Tarquinia (Italy) is reported. In this study, the 24-h steam distillation procedure for essential oil preparation, in terms of different harvesting and extraction times, was applied. The Gas chromatography–mass spectrometry (GC/MS) analysis showed that C. nepeta (L.) Savi subsp. glandulosa (Req.) Ball essential oils from Tarquinia belong to the pulegone-rich chemotype. The analysis of 44 samples revealed that along with pulegone, some other chemicals may participate in exerting the related antifungal activity. The results indicated that for higher activity, the essential oils should be produced with at least a 6-h steam distillation process. Even though it is not so dependent on the period of harvesting, it could be recommended not to harvest the plant in the fruiting stage, since no significant antifungal effect was shown. The maximum essential oil yield was obtained in August, with the highest pulegone percentage. To obtain the oil with a higher content of menthone, September and October should be considered as the optimal periods. Regarding the extraction duration, vegetative stage material gives the oil in the first 3 h, while material from the reproductive phase should be extracted at least at 6 or even 12 h.
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spelling pubmed-61558012018-11-13 Essential Oil Extraction, Chemical Analysis and Anti-Candida Activity of Calamintha nepeta (L.) Savi subsp. glandulosa (Req.) Ball—New Approaches Božović, Mijat Garzoli, Stefania Sabatino, Manuela Pepi, Federico Baldisserotto, Anna Andreotti, Elisa Romagnoli, Carlo Mai, Antonello Manfredini, Stefano Ragno, Rino Molecules Article A comprehensive study on essential oils extracted from different Calamintha nepeta (L.) Savi subsp. glandulosa (Req.) Ball samples from Tarquinia (Italy) is reported. In this study, the 24-h steam distillation procedure for essential oil preparation, in terms of different harvesting and extraction times, was applied. The Gas chromatography–mass spectrometry (GC/MS) analysis showed that C. nepeta (L.) Savi subsp. glandulosa (Req.) Ball essential oils from Tarquinia belong to the pulegone-rich chemotype. The analysis of 44 samples revealed that along with pulegone, some other chemicals may participate in exerting the related antifungal activity. The results indicated that for higher activity, the essential oils should be produced with at least a 6-h steam distillation process. Even though it is not so dependent on the period of harvesting, it could be recommended not to harvest the plant in the fruiting stage, since no significant antifungal effect was shown. The maximum essential oil yield was obtained in August, with the highest pulegone percentage. To obtain the oil with a higher content of menthone, September and October should be considered as the optimal periods. Regarding the extraction duration, vegetative stage material gives the oil in the first 3 h, while material from the reproductive phase should be extracted at least at 6 or even 12 h. MDPI 2017-01-26 /pmc/articles/PMC6155801/ /pubmed/28134788 http://dx.doi.org/10.3390/molecules22020203 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Božović, Mijat
Garzoli, Stefania
Sabatino, Manuela
Pepi, Federico
Baldisserotto, Anna
Andreotti, Elisa
Romagnoli, Carlo
Mai, Antonello
Manfredini, Stefano
Ragno, Rino
Essential Oil Extraction, Chemical Analysis and Anti-Candida Activity of Calamintha nepeta (L.) Savi subsp. glandulosa (Req.) Ball—New Approaches
title Essential Oil Extraction, Chemical Analysis and Anti-Candida Activity of Calamintha nepeta (L.) Savi subsp. glandulosa (Req.) Ball—New Approaches
title_full Essential Oil Extraction, Chemical Analysis and Anti-Candida Activity of Calamintha nepeta (L.) Savi subsp. glandulosa (Req.) Ball—New Approaches
title_fullStr Essential Oil Extraction, Chemical Analysis and Anti-Candida Activity of Calamintha nepeta (L.) Savi subsp. glandulosa (Req.) Ball—New Approaches
title_full_unstemmed Essential Oil Extraction, Chemical Analysis and Anti-Candida Activity of Calamintha nepeta (L.) Savi subsp. glandulosa (Req.) Ball—New Approaches
title_short Essential Oil Extraction, Chemical Analysis and Anti-Candida Activity of Calamintha nepeta (L.) Savi subsp. glandulosa (Req.) Ball—New Approaches
title_sort essential oil extraction, chemical analysis and anti-candida activity of calamintha nepeta (l.) savi subsp. glandulosa (req.) ball—new approaches
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155801/
https://www.ncbi.nlm.nih.gov/pubmed/28134788
http://dx.doi.org/10.3390/molecules22020203
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