New Phenylpropanoid and Coumarin Glycosides from the Stems of Hydrangea paniculata Sieb

A new phenylpropanoid glycoside (1), and two new coumarin glycosides (2, 3), together with two known compounds (4, 5), have been isolated from the stems of Hydrangea paniculata Sieb. Their structures have been determined by spectroscopic and chemical methods. Furthermore, compound 1 (50 μM) exhibite...

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Detalles Bibliográficos
Autores principales: Ma, Jie, Li, Chuang-Jun, Yang, Jing-Zhi, Sun, Hua, Zhang, Dong-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155810/
https://www.ncbi.nlm.nih.gov/pubmed/28106809
http://dx.doi.org/10.3390/molecules22010133
Descripción
Sumario:A new phenylpropanoid glycoside (1), and two new coumarin glycosides (2, 3), together with two known compounds (4, 5), have been isolated from the stems of Hydrangea paniculata Sieb. Their structures have been determined by spectroscopic and chemical methods. Furthermore, compound 1 (50 μM) exhibited significant hepatoprotective activity against N-acetyl-p-aminophenol (APAP)-induced HepG2 cell damage in vitro assays.

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