New Phenylpropanoid and Coumarin Glycosides from the Stems of Hydrangea paniculata Sieb

A new phenylpropanoid glycoside (1), and two new coumarin glycosides (2, 3), together with two known compounds (4, 5), have been isolated from the stems of Hydrangea paniculata Sieb. Their structures have been determined by spectroscopic and chemical methods. Furthermore, compound 1 (50 μM) exhibite...

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Autores principales: Ma, Jie, Li, Chuang-Jun, Yang, Jing-Zhi, Sun, Hua, Zhang, Dong-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155810/
https://www.ncbi.nlm.nih.gov/pubmed/28106809
http://dx.doi.org/10.3390/molecules22010133
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author Ma, Jie
Li, Chuang-Jun
Yang, Jing-Zhi
Sun, Hua
Zhang, Dong-Ming
author_facet Ma, Jie
Li, Chuang-Jun
Yang, Jing-Zhi
Sun, Hua
Zhang, Dong-Ming
author_sort Ma, Jie
collection PubMed
description A new phenylpropanoid glycoside (1), and two new coumarin glycosides (2, 3), together with two known compounds (4, 5), have been isolated from the stems of Hydrangea paniculata Sieb. Their structures have been determined by spectroscopic and chemical methods. Furthermore, compound 1 (50 μM) exhibited significant hepatoprotective activity against N-acetyl-p-aminophenol (APAP)-induced HepG2 cell damage in vitro assays.
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spelling pubmed-61558102018-11-13 New Phenylpropanoid and Coumarin Glycosides from the Stems of Hydrangea paniculata Sieb Ma, Jie Li, Chuang-Jun Yang, Jing-Zhi Sun, Hua Zhang, Dong-Ming Molecules Article A new phenylpropanoid glycoside (1), and two new coumarin glycosides (2, 3), together with two known compounds (4, 5), have been isolated from the stems of Hydrangea paniculata Sieb. Their structures have been determined by spectroscopic and chemical methods. Furthermore, compound 1 (50 μM) exhibited significant hepatoprotective activity against N-acetyl-p-aminophenol (APAP)-induced HepG2 cell damage in vitro assays. MDPI 2017-01-18 /pmc/articles/PMC6155810/ /pubmed/28106809 http://dx.doi.org/10.3390/molecules22010133 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ma, Jie
Li, Chuang-Jun
Yang, Jing-Zhi
Sun, Hua
Zhang, Dong-Ming
New Phenylpropanoid and Coumarin Glycosides from the Stems of Hydrangea paniculata Sieb
title New Phenylpropanoid and Coumarin Glycosides from the Stems of Hydrangea paniculata Sieb
title_full New Phenylpropanoid and Coumarin Glycosides from the Stems of Hydrangea paniculata Sieb
title_fullStr New Phenylpropanoid and Coumarin Glycosides from the Stems of Hydrangea paniculata Sieb
title_full_unstemmed New Phenylpropanoid and Coumarin Glycosides from the Stems of Hydrangea paniculata Sieb
title_short New Phenylpropanoid and Coumarin Glycosides from the Stems of Hydrangea paniculata Sieb
title_sort new phenylpropanoid and coumarin glycosides from the stems of hydrangea paniculata sieb
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155810/
https://www.ncbi.nlm.nih.gov/pubmed/28106809
http://dx.doi.org/10.3390/molecules22010133
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