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ZYZ-772 Prevents Cardiomyocyte Injury by Suppressing Nox4-Derived ROS Production and Apoptosis

Nox-dependent signaling plays critical roles in the development of heart failure, cardiac hypertrophy, and myocardial infarction. NADPH oxidase 4 (Nox4) as a major source of oxidative stress in the heart offers a new therapeutic target in cardiovascular disease. In the present work, a novel flavonoi...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Zhong, Liangjie, Liu, Xinhua, Zhu, Yi Zhun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155929/
https://www.ncbi.nlm.nih.gov/pubmed/28230797
http://dx.doi.org/10.3390/molecules22020331

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