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ZYZ-772 Prevents Cardiomyocyte Injury by Suppressing Nox4-Derived ROS Production and Apoptosis
Nox-dependent signaling plays critical roles in the development of heart failure, cardiac hypertrophy, and myocardial infarction. NADPH oxidase 4 (Nox4) as a major source of oxidative stress in the heart offers a new therapeutic target in cardiovascular disease. In the present work, a novel flavonoi...
Autores principales: | Wang, Ying, Zhong, Liangjie, Liu, Xinhua, Zhu, Yi Zhun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155929/ https://www.ncbi.nlm.nih.gov/pubmed/28230797 http://dx.doi.org/10.3390/molecules22020331 |
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