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Clinical presentation and treatment of cardiac myxoma in 153 patients

Cardiac myxoma (CM) is the most common benign cardiac tumor. We retrospectively reviewed our single center experience in 153 patients with CM over a period 25 years. From November 1993 to May 2017, 153 patients were operated in our institution with diagnosis of a CM. In all patients preoperative, pe...

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Autores principales: Karabinis, Andreas, Samanidis, George, Khoury, Mazen, Stavridis, George, Perreas, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155961/
https://www.ncbi.nlm.nih.gov/pubmed/30213011
http://dx.doi.org/10.1097/MD.0000000000012397
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author Karabinis, Andreas
Samanidis, George
Khoury, Mazen
Stavridis, George
Perreas, Konstantinos
author_facet Karabinis, Andreas
Samanidis, George
Khoury, Mazen
Stavridis, George
Perreas, Konstantinos
author_sort Karabinis, Andreas
collection PubMed
description Cardiac myxoma (CM) is the most common benign cardiac tumor. We retrospectively reviewed our single center experience in 153 patients with CM over a period 25 years. From November 1993 to May 2017, 153 patients were operated in our institution with diagnosis of a CM. In all patients preoperative, perioperative, and postoperative data were recorded including the long-term follow-up. All patients followed up in the outpatient's clinics and echocardiography at regular intervals. Mean age 59 ± 12 years old. There were 104 women and 49 men. Preoperative clinical manifestations of the patients were hemodynamic consequences (47.7%), asymptomatic (46.4%), systemic embolism (4.5%), systemic manifestations-fever (0.7%), and hemoptysis (0.7%). The most common location of CM was in the left atrium in 82.4% patients. Mean tumors diameter was 4.5 ± 1.9 cm. In addition, we were observed that the age of the patients have differences between sex groups women versus men, 60.3 and 54.8 years old respectively (P = .02). On the other hand the tumor size have not differences between the sex groups (P = .56). Combine operations were performed in 24 (15.7%) patients. New cerebrovascular accident was observed in 2 patients post-op. Mean in-hospital stay was 8.02 ± 2.8 days. In-hospital mortality was 1 patient (0.7%) (from sepsis). During median follow-up 3.7 ± 4.3 years CM recurrence was identified in 5 (3.3%) patients. Surgical resection of CMs contributes in an excellent prognosis and associated with low complications and recurrences rate. Regular long-term follow-up is recommended in all patients with CM.
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spelling pubmed-61559612018-11-08 Clinical presentation and treatment of cardiac myxoma in 153 patients Karabinis, Andreas Samanidis, George Khoury, Mazen Stavridis, George Perreas, Konstantinos Medicine (Baltimore) Research Article Cardiac myxoma (CM) is the most common benign cardiac tumor. We retrospectively reviewed our single center experience in 153 patients with CM over a period 25 years. From November 1993 to May 2017, 153 patients were operated in our institution with diagnosis of a CM. In all patients preoperative, perioperative, and postoperative data were recorded including the long-term follow-up. All patients followed up in the outpatient's clinics and echocardiography at regular intervals. Mean age 59 ± 12 years old. There were 104 women and 49 men. Preoperative clinical manifestations of the patients were hemodynamic consequences (47.7%), asymptomatic (46.4%), systemic embolism (4.5%), systemic manifestations-fever (0.7%), and hemoptysis (0.7%). The most common location of CM was in the left atrium in 82.4% patients. Mean tumors diameter was 4.5 ± 1.9 cm. In addition, we were observed that the age of the patients have differences between sex groups women versus men, 60.3 and 54.8 years old respectively (P = .02). On the other hand the tumor size have not differences between the sex groups (P = .56). Combine operations were performed in 24 (15.7%) patients. New cerebrovascular accident was observed in 2 patients post-op. Mean in-hospital stay was 8.02 ± 2.8 days. In-hospital mortality was 1 patient (0.7%) (from sepsis). During median follow-up 3.7 ± 4.3 years CM recurrence was identified in 5 (3.3%) patients. Surgical resection of CMs contributes in an excellent prognosis and associated with low complications and recurrences rate. Regular long-term follow-up is recommended in all patients with CM. Wolters Kluwer Health 2018-09-14 /pmc/articles/PMC6155961/ /pubmed/30213011 http://dx.doi.org/10.1097/MD.0000000000012397 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0.
spellingShingle Research Article
Karabinis, Andreas
Samanidis, George
Khoury, Mazen
Stavridis, George
Perreas, Konstantinos
Clinical presentation and treatment of cardiac myxoma in 153 patients
title Clinical presentation and treatment of cardiac myxoma in 153 patients
title_full Clinical presentation and treatment of cardiac myxoma in 153 patients
title_fullStr Clinical presentation and treatment of cardiac myxoma in 153 patients
title_full_unstemmed Clinical presentation and treatment of cardiac myxoma in 153 patients
title_short Clinical presentation and treatment of cardiac myxoma in 153 patients
title_sort clinical presentation and treatment of cardiac myxoma in 153 patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155961/
https://www.ncbi.nlm.nih.gov/pubmed/30213011
http://dx.doi.org/10.1097/MD.0000000000012397
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