Epigenetic age-predictor for mice based on three CpG sites

Epigenetic clocks for mice were generated based on deep-sequencing analysis of the methylome. Here, we demonstrate that site-specific analysis of DNA methylation levels by pyrosequencing at only three CG dinucleotides (CpGs) in the genes Prima1, Hsf4, and Kcns1 facilitates precise estimation of chro...

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Detalles Bibliográficos
Autores principales: Han, Yang, Eipel, Monika, Franzen, Julia, Sakk, Vadim, Dethmers-Ausema, Bertien, Yndriago, Laura, Izeta, Ander, de Haan, Gerald, Geiger, Hartmut, Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156076/
https://www.ncbi.nlm.nih.gov/pubmed/30142075
http://dx.doi.org/10.7554/eLife.37462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156076/
https://www.ncbi.nlm.nih.gov/pubmed/30142075
http://dx.doi.org/10.7554/eLife.37462

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