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Epigenetic age-predictor for mice based on three CpG sites
Epigenetic clocks for mice were generated based on deep-sequencing analysis of the methylome. Here, we demonstrate that site-specific analysis of DNA methylation levels by pyrosequencing at only three CG dinucleotides (CpGs) in the genes Prima1, Hsf4, and Kcns1 facilitates precise estimation of chro...
Autores principales: | Han, Yang, Eipel, Monika, Franzen, Julia, Sakk, Vadim, Dethmers-Ausema, Bertien, Yndriago, Laura, Izeta, Ander, de Haan, Gerald, Geiger, Hartmut, Wagner, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156076/ https://www.ncbi.nlm.nih.gov/pubmed/30142075 http://dx.doi.org/10.7554/eLife.37462 |
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