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Mechanisms of Regulated and Dysregulated CARD11 Signaling in Adaptive Immunity and Disease
CARD11 functions as a key signaling scaffold that controls antigen-induced lymphocyte activation during the adaptive immune response. Somatic mutations in CARD11 are frequently found in Non-Hodgkin lymphoma, and at least three classes of germline CARD11 mutations have been described as the basis for...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156143/ https://www.ncbi.nlm.nih.gov/pubmed/30283447 http://dx.doi.org/10.3389/fimmu.2018.02105 |