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Effect of Vitis vinifera hydroalcoholic extract against oxaliplatin neurotoxicity: in vitro and in vivo evidence

Oxaliplatin treatment is associated with the development of a dose-limiting painful neuropathy impairing patient’s quality of life. Since oxidative unbalance is a relevant mechanism of oxaliplatin neurotoxicity, we assessed the potential antioxidant properties of Vitis vinifera extract in reducing o...

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Detalles Bibliográficos
Autores principales: Micheli, Laura, Mattoli, Luisa, Maidecchi, Anna, Pacini, Alessandra, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156221/
https://www.ncbi.nlm.nih.gov/pubmed/30254294
http://dx.doi.org/10.1038/s41598-018-32691-w