Toxoplasma Effector TgIST Targets Host IDO1 to Antagonize the IFN-γ-Induced Anti-parasitic Response in Human Cells

Toxoplasma gondii is an important human and animal pathogen that causes life-threatening toxoplasmosis. Interferon-γ (IFN-γ) is critical for anti-T. gondii cell-autonomous immunity in both humans and mice. To proliferate efficiently within the hosts, virulent strains of T. gondii can suppress IFN-γ-...

Descripción completa

Detalles Bibliográficos
Autores principales: Bando, Hironori, Sakaguchi, Naoya, Lee, Youngae, Pradipta, Ariel, Ma, Ji Su, Tanaka, Shun, Lai, De-Hua, Liu, Jianfa, Lun, Zhao-Rong, Nishikawa, Yoshifumi, Sasai, Miwa, Yamamoto, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156249/
https://www.ncbi.nlm.nih.gov/pubmed/30283439
http://dx.doi.org/10.3389/fimmu.2018.02073

Ejemplares similares

Ejemplares similares