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Modeling of mesenchymal hybrid epithelial state and phenotypic transitions in EMT and MET processes of cancer cells
Based on the transcriptional regulatory mechanisms between microRNA-200 and transcription factor ZEB in an individual cancer cell, a minimal dynamic model is proposed to study the epithelial-mesenchymal transition (EMT) and mesenchymal-epithelial transition (MET) processes of cancer cells. It is sho...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156327/ https://www.ncbi.nlm.nih.gov/pubmed/30254295 http://dx.doi.org/10.1038/s41598-018-32737-z |