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Microenvironmental niche divergence shapes BRCA1-dysregulated ovarian cancer morphological plasticity

How tumor microenvironmental forces shape plasticity of cancer cell morphology is poorly understood. Here, we conduct automated histology image and spatial statistical analyses in 514 high grade serous ovarian samples to define cancer morphological diversification within the spatial context of the m...

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Detalles Bibliográficos
Autores principales:	Heindl, Andreas, Khan, Adnan Mujahid, Rodrigues, Daniel Nava, Eason, Katherine, Sadanandam, Anguraj, Orbegoso, Cecilia, Punta, Marco, Sottoriva, Andrea, Lise, Stefano, Banerjee, Susana, Yuan, Yinyin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156340/ https://www.ncbi.nlm.nih.gov/pubmed/30254278 http://dx.doi.org/10.1038/s41467-018-06130-3

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