CXCL6‐EGFR‐induced Kupffer cells secrete TGF‐β1 promoting hepatic stellate cell activation via the SMAD2/BRD4/C‐MYC/EZH2 pathway in liver fibrosis

Liver fibrosis is the excessive accumulation of extracellular matrix proteins in response to the inflammatory response that accompanies tissue injury, which at an advanced stage can lead to cirrhosis and even liver failure. This study investigated the role of the CXC chemokine CXCL6 (GCP‐2) in liver...

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Detalles Bibliográficos
Autores principales: Cai, Xiaobo, Li, Zhenghong, Zhang, Qidi, Qu, Yin, Xu, Mingyi, Wan, Xinjian, Lu, Lungen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156397/
https://www.ncbi.nlm.nih.gov/pubmed/30106235
http://dx.doi.org/10.1111/jcmm.13787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156397/
https://www.ncbi.nlm.nih.gov/pubmed/30106235
http://dx.doi.org/10.1111/jcmm.13787

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