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Plasmodium co-infection protects against chikungunya virus-induced pathologies

Co-infection with Plasmodium and chikungunya virus (CHIKV) has been reported in humans, but the impact of co-infection on pathogenesis remains unclear. Here, we show that prior exposure to Plasmodium suppresses CHIKV-associated pathologies in mice. Mechanistically, Plasmodium infection induces IFNγ,...

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Detalles Bibliográficos
Autores principales: Teo, Teck-Hui, Lum, Fok-Moon, Ghaffar, Khairunnisa, Chan, Yi-Hao, Amrun, Siti Naqiah, Tan, Jeslin J. L., Lee, Cheryl Y. P., Chua, Tze-Kwang, Carissimo, Guillaume, Lee, Wendy W. L., Claser, Carla, Rajarethinam, Ravisankar, Rénia, Laurent, Ng, Lisa F. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156405/
https://www.ncbi.nlm.nih.gov/pubmed/30254309
http://dx.doi.org/10.1038/s41467-018-06227-9

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