FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration

Intervertebral disk (IVD) degeneration is a prevalent age‐associated musculoskeletal disorder and a major cause of chronic low back pain. Aging is the main risk factor for the disease, but the molecular mechanisms regulating IVD homeostasis during aging are unknown. The aim of this study was to inve...

Descripción completa

Detalles Bibliográficos
Autores principales: Alvarez‐Garcia, Oscar, Matsuzaki, Tokio, Olmer, Merissa, Miyata, Kohei, Mokuda, Sho, Sakai, Daisuke, Masuda, Koichi, Asahara, Hiroshi, Lotz, Martin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156454/
https://www.ncbi.nlm.nih.gov/pubmed/29963746
http://dx.doi.org/10.1111/acel.12800

Ejemplares similares

Ejemplares similares