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CCAR‐1 is a negative regulator of the heat‐shock response in Caenorhabditis elegans

Defects in protein quality control during aging are central to many human diseases, and strategies are needed to better understand mechanisms of controlling the quality of the proteome. The heat‐shock response (HSR) is a conserved survival mechanism mediated by the transcription factor HSF1 which fu...

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Detalles Bibliográficos
Autores principales: Brunquell, Jessica, Raynes, Rachel, Bowers, Philip, Morris, Stephanie, Snyder, Alana, Lugano, Doreen, Deonarine, Andrew, Westerheide, Sandy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156500/
https://www.ncbi.nlm.nih.gov/pubmed/30003683
http://dx.doi.org/10.1111/acel.12813