N-terminal truncations on L1 proteins of human papillomaviruses promote their soluble expression in Escherichia coli and self-assembly in vitro

Human papillomavirus (HPV) is the causative agent in genital warts and nearly all cervical, anogenital, and oropharyngeal cancers. Nine HPV types (6, 11, 16, 18, 31, 33, 45, 52, and 58) are associated with about 90% of cervical cancers and 90% of genital warts. HPV neutralization by vaccine-elicited...

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Detalles Bibliográficos
Autores principales: Wei, Minxi, Wang, Daning, Li, Zhihai, Song, Shuo, Kong, Xianglin, Mo, Xiaobing, Yang, Yurou, He, Maozhou, Li, Zhongyi, Huang, Bo, Lin, Zhijie, Pan, Huirong, Zheng, Qingbing, Yu, Hai, Gu, Ying, Zhang, Jun, Li, Shaowei, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156512/
https://www.ncbi.nlm.nih.gov/pubmed/30254257
http://dx.doi.org/10.1038/s41426-018-0158-2

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