Cargando…

The Contribution and Therapeutic Potential of Epigenetic Modifications in Alzheimer’s Disease

Alzheimer’s disease is a progressive neurodegenerative disorder, affecting 50 million people worldwide, for which there is no cure, or effective treatment. Individuals suffering from Alzheimer’s show a decline in cognition over time beginning with memory loss and ultimately leading to severe dementi...

Descripción completa

Detalles Bibliográficos
Autor principal:	Wood, Ian C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156518/ https://www.ncbi.nlm.nih.gov/pubmed/30283297 http://dx.doi.org/10.3389/fnins.2018.00649

Ejemplares similares

Epigenetic Modifications in Alzheimer’s Neuropathology and Therapeutics
por: Esposito, Michelle, et al.
Publicado: (2019)

Epigenetics in Alzheimer’s Disease
por: Gao, Xiaodie, et al.
Publicado: (2022)

Amyloid-clearing proteins and their epigenetic regulation as a therapeutic target in Alzheimer’s disease
por: Nalivaeva, Natalia N., et al.
Publicado: (2014)

Epigenetic Alterations in Alzheimer’s Disease
por: Sanchez-Mut, Jose V., et al.
Publicado: (2015)

Aluminum and its potential contribution to Alzheimer's disease (AD)
por: Bhattacharjee, Surjyadipta, et al.
Publicado: (2014)

Gamma Oscillations in Alzheimer’s Disease and Their Potential Therapeutic Role
por: Traikapi, Artemis, et al.
Publicado: (2021)

Microglia in Alzheimer’s disease: pathogenesis, mechanisms, and therapeutic potentials
por: Miao, Jifei, et al.
Publicado: (2023)

Epigenetic regulation of synaptic disorder in Alzheimer’s disease
por: Chen, Zhiying, et al.
Publicado: (2022)

Potential Epigenetic-Based Therapeutic Targets for Glioma
por: Zang, Lanlan, et al.
Publicado: (2018)

Potential contributions of trace amines in Alzheimer’s disease and therapeutic prospects
por: Dhakal, Sudip, et al.
Publicado: (2020)

Modifications and Trafficking of APP in the Pathogenesis of Alzheimer’s Disease
por: Wang, Xin, et al.
Publicado: (2017)

Clinical relevance of biomarkers, new therapeutic approaches, and role of post-translational modifications in the pathogenesis of Alzheimer’s disease
por: Mumtaz, Ibtisam, et al.
Publicado: (2022)

Inhibition of Amyloid-Beta Production, Associated Neuroinflammation, and Histone Deacetylase 2-Mediated Epigenetic Modifications Prevent Neuropathology in Alzheimer’s Disease in vitro Model
por: Atluri, Venkata Subba Rao, et al.
Publicado: (2020)

Cardiometabolic Modification of Amyloid Beta in Alzheimer’s Disease Pathology
por: Hefner, Marleigh, et al.
Publicado: (2021)

The Emerging Roles and Therapeutic Potential of Soluble TREM2 in Alzheimer’s Disease
por: Zhong, Li, et al.
Publicado: (2019)

Sirtuins as Potential Therapeutic Targets for Mitigating Neuroinflammation Associated With Alzheimer’s Disease
por: Fernando, Kurukulasooriya Kavindya Madushani, et al.
Publicado: (2021)

Neuromodulating roles of estrogen and phytoestrogens in cognitive therapeutics through epigenetic modifications during aging
por: Singh, Padmanabh, et al.
Publicado: (2022)

Inflammation and Insulin Resistance as Risk Factors and Potential Therapeutic Targets for Alzheimer’s Disease
por: Vinuesa, Angeles, et al.
Publicado: (2021)

Tubulin and Tubulin Posttranslational Modifications in Alzheimer’s Disease and Vascular Dementia
por: Santiago-Mujika, Estibaliz, et al.
Publicado: (2021)

Metabolic Dysregulation Contributes to the Progression of Alzheimer’s Disease
por: Yan, Xu, et al.
Publicado: (2020)

Editorial: Protein modifications in epigenetic dysfunctional diseases: mechanisms and potential therapeutic strategies
por: Ji, Jing, et al.
Publicado: (2023)

Epigenetic Modifications as Therapeutic Targets
por: Kelly, Theresa K, et al.
Publicado: (2010)

Transcriptional Dysregulation and Post-translational Modifications in Polyglutamine Diseases: From Pathogenesis to Potential Therapeutic Strategies
por: Xiang, Chunchen, et al.
Publicado: (2018)

The contribution of mitochondria-associated endoplasmic reticulum membranes (MAMs) dysfunction in Alzheimer’s disease and the potential countermeasure
por: Li, Zehui, et al.
Publicado: (2023)

Epigenetic modifications of chronic hypoxia-mediated neurodegeneration in Alzheimer’s disease
por: Liu, Hui, et al.
Publicado: (2014)

The Ubiquitin-Proteasome System: Potential Therapeutic Targets for Alzheimer’s Disease and Spinal Cord Injury
por: Gong, Bing, et al.
Publicado: (2016)

The Therapeutic and Diagnostic Potential of Amyloid β Oligomers Selective Antibodies to Treat Alzheimer’s Disease
por: Viola, Kirsten L., et al.
Publicado: (2022)

GW5074 Increases Microglial Phagocytic Activities: Potential Therapeutic Direction for Alzheimer’s Disease
por: Connor, Sarah M., et al.
Publicado: (2022)

Network pharmacology identify intersection genes of quercetin and Alzheimer’s disease as potential therapeutic targets
por: Wei, Caihui, et al.
Publicado: (2022)

EAAT2 as a therapeutic research target in Alzheimer's disease: A systematic review
por: Wood, Oliver W. G., et al.
Publicado: (2022)

RNA N6-Methyladenosine Modifications and Its Roles in Alzheimer’s Disease
por: Zhang, Runjiao, et al.
Publicado: (2022)

Tau pathology epigenetically remodels the neuron-glial cross-talk in Alzheimer’s disease
por: Zhou, Lan-Ting, et al.
Publicado: (2023)

The Role of Epigenetic Modifications in Neurotoxicity Induced by Neonatal General Anesthesia
por: Ma, Lin-Hui, et al.
Publicado: (2022)

Endocannabinoid signaling and epigenetics modifications in the neurobiology of stress-related disorders
por: Coelho, Arthur A., et al.
Publicado: (2023)

Astrocytes’ Contribution to Adult Neurogenesis in Physiology and Alzheimer’s Disease
por: Cassé, Frédéric, et al.
Publicado: (2018)

Inflamma-MicroRNAs in Alzheimer’s Disease: From Disease Pathogenesis to Therapeutic Potentials
por: Liang, Yuanyuan, et al.
Publicado: (2021)

The Epigenetics of Alzheimer’s Disease: Factors and Therapeutic Implications
por: Liu, Xiaolei, et al.
Publicado: (2018)

Microglia Polarization in Alzheimer’s Disease: Mechanisms and a Potential Therapeutic Target
por: Wang, Qinqin, et al.
Publicado: (2021)

Neuronal ApoE4 in Alzheimer’s disease and potential therapeutic targets
por: Zhang, Lan, et al.
Publicado: (2023)

Alzheimer’s Disease and microRNA-132: A Widespread Pathological Factor and Potential Therapeutic Target
por: Zhang, Meng, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5un2gafqe278ei4ncm7rt8v2gf