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Gene expression‐based drug repurposing to target aging

Aging is the largest risk factor for a variety of noncommunicable diseases. Model organism studies have shown that genetic and chemical perturbations can extend both lifespan and healthspan. Aging is a complex process, with parallel and interacting mechanisms contributing to its aetiology, posing a...

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Detalles Bibliográficos
Autores principales: Dönertaş, Handan Melike, Fuentealba Valenzuela, Matías, Partridge, Linda, Thornton, Janet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156541/
https://www.ncbi.nlm.nih.gov/pubmed/29959820
http://dx.doi.org/10.1111/acel.12819

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