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Gene expression‐based drug repurposing to target aging
Aging is the largest risk factor for a variety of noncommunicable diseases. Model organism studies have shown that genetic and chemical perturbations can extend both lifespan and healthspan. Aging is a complex process, with parallel and interacting mechanisms contributing to its aetiology, posing a...
Autores principales: | Dönertaş, Handan Melike, Fuentealba Valenzuela, Matías, Partridge, Linda, Thornton, Janet M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156541/ https://www.ncbi.nlm.nih.gov/pubmed/29959820 http://dx.doi.org/10.1111/acel.12819 |
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