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Analysis of extracellular mRNA in human urine reveals splice variant biomarkers of muscular dystrophies
Urine contains extracellular RNA (exRNA) markers of urogenital cancers. However, the capacity of genetic material in urine to identify systemic diseases is unknown. Here we describe exRNA splice products in human urine as a source of biomarkers for the two most common forms of muscular dystrophies,...
Autores principales: | Antoury, Layal, Hu, Ningyan, Balaj, Leonora, Das, Sudeshna, Georghiou, Sofia, Darras, Basil, Clark, Tim, Breakefield, Xandra O., Wheeler, Thurman M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156576/ https://www.ncbi.nlm.nih.gov/pubmed/30254196 http://dx.doi.org/10.1038/s41467-018-06206-0 |
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