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Design and development of a biorelevant simulated human lung fluid
Biorelevant fluids are required to enable meaningful in vitro experimental determinations of the biopharmaceutical properties of inhaled medicines, e.g. drug solubility, particle dissolution, cellular uptake. Our aim was to develop a biorelevant simulated lung fluid (SLF) with a well-defined composi...
Autores principales: | Hassoun, Mireille, Royall, Paul G., Parry, Mark, Harvey, Richard D., Forbes, Ben |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156579/ https://www.ncbi.nlm.nih.gov/pubmed/30283501 http://dx.doi.org/10.1016/j.jddst.2018.08.006 |
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