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Frequency and phenotype consequence of APOC3 rare variants in patients with very low triglyceride levels

BACKGROUND: High levels of triglycerides (TG ≥200 mg/dL) are an emerging risk factor for cardiovascular disease. Conversely, very low levels of TG are associated with decreased risk for cardiovascular disease. Precision medicine aims to capitalize on recent findings that rare variants such as APOC3...

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Detalles Bibliográficos
Autores principales: Crawford, Dana C., Restrepo, Nicole A., Diggins, Kirsten E., Farber-Eger, Eric, Wells, Quinn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156840/
https://www.ncbi.nlm.nih.gov/pubmed/30255797
http://dx.doi.org/10.1186/s12920-018-0387-1