Cargando…

Gene-methylation epistatic analyses via the W-test identifies enriched signals of neuronal genes in patients undergoing lipid-control treatment

An increasing number of studies are focused on the epigenetic regulation of DNA to affect gene expression without modifications to the DNA sequence. Methylation plays an important role in shaping disease traits; however, previous studies were mainly experiment, based, resulting in few reports that m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Rui, Weng, Haoyi, Men, Ruoting, Xia, Xiaoxuan, Chong, Ka Chun, Wu, William K. K., Zee, Benny Chung-Ying, Wang, Maggie Haitian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156903/ https://www.ncbi.nlm.nih.gov/pubmed/30263051 http://dx.doi.org/10.1186/s12919-018-0143-8

Ejemplares similares

Incorporating methylation genome information improves prediction accuracy for drug treatment responses
por: Xia, Xiaoxuan, et al.
Publicado: (2018)

A clustering approach to identify rare variants associated with hypertension
por: Sun, Rui, et al.
Publicado: (2016)

Identification of epistatic interactions between the human RNA demethylases FTO and ALKBH5 with gene set enrichment analysis informed by differential methylation
por: Piette, Elizabeth R., et al.
Publicado: (2018)

A fast and powerful W-test for pairwise epistasis testing
por: Wang, Maggie Haitian, et al.
Publicado: (2016)

A fast and powerful W-test for pairwise epistasis testing
por: Wang, Maggie Haitian, et al.
Publicado: (2016)

Detecting epistatic interactions contributing to human gene expression using the CEPH family data
por: Li, Hua, et al.
Publicado: (2007)

Searching for epistatic interactions in nuclear families using conditional linkage analysis
por: Shah, Svati H, et al.
Publicado: (2005)

wtest: an integrated R package for genetic epistasis testing
por: Sun, Rui, et al.
Publicado: (2019)

Evaluating epistatic interaction signals in complex traits using quantitative traits
por: Mukherjee, Odity, et al.
Publicado: (2009)

Discovering pure gene-environment interactions in blood pressure genome-wide association studies data: a two-step approach incorporating new statistics
por: Wang, Maggie Haitian, et al.
Publicado: (2014)

A statistical method utilizing information of imported cases to estimate the transmissibility for an influenza pandemic
por: Chong, Ka Chun, et al.
Publicado: (2017)

Identifying Meteorological Drivers for the Seasonal Variations of Influenza Infections in a Subtropical City — Hong Kong
por: Chong, Ka Chun, et al.
Publicado: (2015)

bNEAT: a Bayesian network method for detecting epistatic interactions in genome-wide association studies
por: Han, Bing, et al.
Publicado: (2011)

miR2Gene: pattern discovery of single gene, multiple genes, and pathways by enrichment analysis of their microRNA regulators
por: Qiu, Chengxiang, et al.
Publicado: (2011)

SNP-PRAGE: SNP-based parametric robust analysis of gene set enrichment
por: Lee, Jaehoon, et al.
Publicado: (2011)

Comparing gene annotation enrichment tools for functional modeling of agricultural microarray data
por: Berg, Bart HJ van den, et al.
Publicado: (2009)

Concordant integrative gene set enrichment analysis of multiple large-scale two-sample expression data sets
por: Lai, Yinglei, et al.
Publicado: (2014)

A partition-based approach to identify gene-environment interactions in genome wide association studies
por: Fan, Ruixue, et al.
Publicado: (2014)

PAGED: a pathway and gene-set enrichment database to enable molecular phenotype discoveries
por: Huang, Hui, et al.
Publicado: (2012)

Gene set enrichment analysis of RNA-Seq data: integrating differential expression and splicing
por: Wang, Xi, et al.
Publicado: (2013)

Enrichment analysis of genetic association in genes and pathways by aggregating signals from both rare and common variants
por: Yang, Wei, et al.
Publicado: (2011)

A Prism Vote method for individualized risk prediction of traits in genotype data of Multi-population
por: Xia, Xiaoxuan, et al.
Publicado: (2022)

Selection for Protein Stability Enriches for Epistatic Interactions
por: Posfai, Anna, et al.
Publicado: (2018)

Joint linkage and imprinting analyses of GAW15 rheumatoid arthritis and gene expression data
por: Zhou, Xiaojun, et al.
Publicado: (2007)

Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium
por: Verma, Shefali Setia, et al.
Publicado: (2016)

Gene × gene and gene × environment interactions for complex disorders
por: Culverhouse, Robert, et al.
Publicado: (2007)

Network-based functional enrichment
por: Poirel, Christopher L, et al.
Publicado: (2011)

An adaptive gene-based test for methylation data
por: Wu, Chong, et al.
Publicado: (2018)

Collapsing-based and kernel-based single-gene analyses applied to Genetic Analysis Workshop 17 mini-exome data
por: Li, Lun, et al.
Publicado: (2011)

Genome-wide association analyses of the 15(th )QTL-MAS workshop data using mixed model based single locus regression analysis
por: Fu, Wei-Xuan, et al.
Publicado: (2012)

Epistatic interactions of CDKN2B-TCF7L2 for risk of type 2 diabetes and of CDKN2B-JAZF1 for triglyceride/high-density lipoprotein ratio longitudinal change: evidence from the Framingham Heart Study
por: An, Ping, et al.
Publicado: (2009)

DoOPSearch: a web-based tool for finding and analysing common conserved motifs in the promoter regions of different chordate and plant genes
por: Sebestyén, Endre, et al.
Publicado: (2009)

Stability of variable importance scores and rankings using statistical learning tools on single-nucleotide polymorphisms and risk factors involved in gene × gene and gene × environment interactions
por: Nicodemus, Kristin K, et al.
Publicado: (2007)

Detection of gene orthology from gene co-expression and protein interaction networks
por: Towfic, Fadi, et al.
Publicado: (2010)

Epistatically Interacting Substitutions Are Enriched during Adaptive Protein Evolution
por: Gong, Lizhi Ian, et al.
Publicado: (2014)

Growth of Novel Epistatic Interactions by Gene Duplication
por: Jiang, Huifeng, et al.
Publicado: (2011)

Incorporating biological knowledge in the search for gene × gene interaction in genome-wide association studies
por: Manning, Alisa K, et al.
Publicado: (2009)

Epidemiological changes in measles infections in southern China between 2009 and 2016: a retrospective database analysis
por: Zheng, Huizhen, et al.
Publicado: (2020)

Evaluating gene × gene and gene × smoking interaction in rheumatoid arthritis using candidate genes in GAW15
por: Mei, Ling, et al.
Publicado: (2007)

Linkage and association analyses of principal components in expression data
por: Hinrichs, Anthony L, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_6h0fgm4t3goollr0dkohhcg87m