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Do changes in DNA methylation mediate or interact with SNP variation? A pharmacoepigenetic analysis

BACKGROUND: In studies with multi-omics data available, there is an opportunity to investigate interdependent mechanisms of biological causality. The GAW20 data set includes both DNA genotype and methylation measures before and after fenofibrate treatment. Using change in triglyceride (TG) levels pr...

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Detalles Bibliográficos
Autores principales: Fisher, Virginia A., Wang, Lan, Deng, Xuan, Sarnowski, Chloé, Cupples, L. Adrienne, Liu, Ching-Ti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156904/
https://www.ncbi.nlm.nih.gov/pubmed/30255765
http://dx.doi.org/10.1186/s12863-018-0635-6