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Methods to evaluate rare variants gene-age interaction for triglycerides

Triglycerides are an important measure of heart health. Although more than 90 genes have been found to be associated to lipids, they only explain 12 to 15% of the variance in lipid levels. Evidence suggests that age may interact with the genetic effect on lipid levels. Existing methods to detect the...

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Detalles Bibliográficos
Autores principales: Gao, Tony Huayang, Zhang, Jianjun, Miguelangel, Diaz Medina, Wang, Xuexia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156913/
https://www.ncbi.nlm.nih.gov/pubmed/30263050
http://dx.doi.org/10.1186/s12919-018-0136-7