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Rare variants in the splicing regulatory elements of EXOC3L4 are associated with brain glucose metabolism in Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases that causes problems related to brain function. To some extent it is understood on a molecular level how AD arises, however there are a lack of biomarkers that can be used for early diagnosis. Two popular metho...

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Detalles Bibliográficos
Autores principales:	Miller, Jason E., Shivakumar, Manu K., Lee, Younghee, Han, Seonggyun, Horgousluoglu, Emrin, Risacher, Shannon L., Saykin, Andrew J., Nho, Kwangsik, Kim, Dokyoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156983/ https://www.ncbi.nlm.nih.gov/pubmed/30255815 http://dx.doi.org/10.1186/s12920-018-0390-6

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