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Distinguishing prognostic and predictive biomarkers: an information theoretic approach
MOTIVATION: The identification of biomarkers to support decision-making is central to personalized medicine, in both clinical and research scenarios. The challenge can be seen in two halves: identifying predictive markers, which guide the development/use of tailored therapies; and identifying progno...
Autores principales: | Sechidis, Konstantinos, Papangelou, Konstantinos, Metcalfe, Paul D, Svensson, David, Weatherall, James, Brown, Gavin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157098/ https://www.ncbi.nlm.nih.gov/pubmed/29726967 http://dx.doi.org/10.1093/bioinformatics/bty357 |
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