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Distinguishing prognostic and predictive biomarkers: an information theoretic approach

MOTIVATION: The identification of biomarkers to support decision-making is central to personalized medicine, in both clinical and research scenarios. The challenge can be seen in two halves: identifying predictive markers, which guide the development/use of tailored therapies; and identifying progno...

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Detalles Bibliográficos
Autores principales: Sechidis, Konstantinos, Papangelou, Konstantinos, Metcalfe, Paul D, Svensson, David, Weatherall, James, Brown, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157098/
https://www.ncbi.nlm.nih.gov/pubmed/29726967
http://dx.doi.org/10.1093/bioinformatics/bty357