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Reliability of genomic predictions of complex human phenotypes

Genome-wide association studies have helped us identify a wealth of genetic variants associated with complex human phenotypes. Because most variants explain a small portion of the total phenotypic variation, however, marker-based studies remain limited in their ability to predict such phenotypes. He...

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Detalles Bibliográficos
Autores principales:	Porto, Arthur, Peralta, Juan M., Blackburn, Nicholas B., Blangero, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157117/ https://www.ncbi.nlm.nih.gov/pubmed/30275897 http://dx.doi.org/10.1186/s12919-018-0138-5

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