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Investigating potential causal relationships between SNPs, DNA methylation and HDL

Using data on 680 patients from the GAW20 real data set, we conducted Mendelian randomization (MR) studies to explore the causal relationships between methylation levels at selected probes (cytosine-phosphate-guanine sites [CpGs]) and high-density lipoprotein (HDL) changes (ΔHDL) using single-nucleo...

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Detalles Bibliográficos
Autores principales: Jiang, Lai, Zhao, Kaiqiong, Klein, Kathleen, Canty, Angelo J., Oualkacha, Karim, Greenwood, Celia M. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157157/
https://www.ncbi.nlm.nih.gov/pubmed/30275877
http://dx.doi.org/10.1186/s12919-018-0117-x