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Integrative pathway-based survival prediction utilizing the interaction between gene expression and DNA methylation in breast cancer
BACKGROUND: Integrative analysis on multi-omics data has gained much attention recently. To investigate the interactive effect of gene expression and DNA methylation on cancer, we propose a directed random walk-based approach on an integrated gene-gene graph that is guided by pathway information. ME...
Autores principales: | Kim, So Yeon, Kim, Tae Rim, Jeong, Hyun-Hwan, Sohn, Kyung-Ah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157196/ https://www.ncbi.nlm.nih.gov/pubmed/30255812 http://dx.doi.org/10.1186/s12920-018-0389-z |
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