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A Bayesian mixed modeling approach for estimating heritability

BACKGROUND: A Bayesian mixed model approach using integrated nested Laplace approximations (INLA) allows us to construct flexible models that can account for pedigree structure. Using these models, we estimate genome-wide patterns of DNA methylation heritability (h(2)), which are currently not well...

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Detalles Bibliográficos
Autores principales: Nustad, Haakon E., Page, Christian M., Reiner, Andrew H., Zucknick, Manuela, LeBlanc, Marissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157283/
https://www.ncbi.nlm.nih.gov/pubmed/30275883
http://dx.doi.org/10.1186/s12919-018-0131-z