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A Bayesian mixed modeling approach for estimating heritability
BACKGROUND: A Bayesian mixed model approach using integrated nested Laplace approximations (INLA) allows us to construct flexible models that can account for pedigree structure. Using these models, we estimate genome-wide patterns of DNA methylation heritability (h(2)), which are currently not well...
Autores principales: | Nustad, Haakon E., Page, Christian M., Reiner, Andrew H., Zucknick, Manuela, LeBlanc, Marissa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157283/ https://www.ncbi.nlm.nih.gov/pubmed/30275883 http://dx.doi.org/10.1186/s12919-018-0131-z |
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