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A graph-based filtering method for top-down mass spectral identification

BACKGROUND: Database search has been the main approach for proteoform identification by top-down tandem mass spectrometry. However, when the target proteoform that produced the spectrum contains post-translational modifications (PTMs) and/or mutations, it is quite time consuming to align a query spe...

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Detalles Bibliográficos
Autores principales: Yang, Runmin, Zhu, Daming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157290/
https://www.ncbi.nlm.nih.gov/pubmed/30255788
http://dx.doi.org/10.1186/s12864-018-5026-x