MicroRNAs Enable mRNA Therapeutics to Selectively Program Cancer Cells to Self-Destruct

The advent of therapeutic mRNAs significantly increases the possibilities of protein-based biologics beyond those that can be synthesized by recombinant technologies (eg, monoclonal antibodies, extracellular enzymes, and cytokines). In addition to their application in the areas of vaccine developmen...

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Detalles Bibliográficos
Autores principales: Jain, Ruchi, Frederick, Josh P., Huang, Eric Y., Burke, Kristine E., Mauger, David M., Andrianova, Elizaveta A., Farlow, Sam J., Siddiqui, Summar, Pimentel, Jeffrey, Cheung-Ong, Kahlin, McKinney, Kristine M., Köhrer, Caroline, Moore, Melissa J., Chakraborty, Tirtha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157376/
https://www.ncbi.nlm.nih.gov/pubmed/30088967
http://dx.doi.org/10.1089/nat.2018.0734

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