Bone Health and Natural Products- An Insight

Bone metabolism involves a complex balance between matrix deposition, mineralization, and resorption. Numerous evidences have revealed that dietary components and phytoconstituents can influence these processes, through inhibition of bone resorption, thus exhibiting beneficial effects on the skeleto...

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Autores principales: Suvarna, Vasanti, Sarkar, Megha, Chaubey, Pramila, Khan, Tabassum, Sherje, Atul, Patel, Kavitkumar, Dravyakar, Bhushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157411/
https://www.ncbi.nlm.nih.gov/pubmed/30283334
http://dx.doi.org/10.3389/fphar.2018.00981
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author Suvarna, Vasanti
Sarkar, Megha
Chaubey, Pramila
Khan, Tabassum
Sherje, Atul
Patel, Kavitkumar
Dravyakar, Bhushan
author_facet Suvarna, Vasanti
Sarkar, Megha
Chaubey, Pramila
Khan, Tabassum
Sherje, Atul
Patel, Kavitkumar
Dravyakar, Bhushan
author_sort Suvarna, Vasanti
collection PubMed
description Bone metabolism involves a complex balance between matrix deposition, mineralization, and resorption. Numerous evidences have revealed that dietary components and phytoconstituents can influence these processes, through inhibition of bone resorption, thus exhibiting beneficial effects on the skeleton. Various traditional herbal formulae in ayurvedic and Chinese medicine have shown demonstrable benefits in pharmacological models of osteoporosis. The present review discusses normal bone metabolism and disorders caused by bone disruption, with particular reference to osteoporosis and current therapeutic treatment. Furthermore the effects of constituents from natural products on bone tissue are explained, with relevant evidences of efficacy in various experimental models.
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spelling pubmed-61574112018-10-03 Bone Health and Natural Products- An Insight Suvarna, Vasanti Sarkar, Megha Chaubey, Pramila Khan, Tabassum Sherje, Atul Patel, Kavitkumar Dravyakar, Bhushan Front Pharmacol Pharmacology Bone metabolism involves a complex balance between matrix deposition, mineralization, and resorption. Numerous evidences have revealed that dietary components and phytoconstituents can influence these processes, through inhibition of bone resorption, thus exhibiting beneficial effects on the skeleton. Various traditional herbal formulae in ayurvedic and Chinese medicine have shown demonstrable benefits in pharmacological models of osteoporosis. The present review discusses normal bone metabolism and disorders caused by bone disruption, with particular reference to osteoporosis and current therapeutic treatment. Furthermore the effects of constituents from natural products on bone tissue are explained, with relevant evidences of efficacy in various experimental models. Frontiers Media S.A. 2018-09-19 /pmc/articles/PMC6157411/ /pubmed/30283334 http://dx.doi.org/10.3389/fphar.2018.00981 Text en Copyright © 2018 Suvarna, Sarkar, Chaubey, Khan, Sherje, Patel and Dravyakar. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Suvarna, Vasanti
Sarkar, Megha
Chaubey, Pramila
Khan, Tabassum
Sherje, Atul
Patel, Kavitkumar
Dravyakar, Bhushan
Bone Health and Natural Products- An Insight
title Bone Health and Natural Products- An Insight
title_full Bone Health and Natural Products- An Insight
title_fullStr Bone Health and Natural Products- An Insight
title_full_unstemmed Bone Health and Natural Products- An Insight
title_short Bone Health and Natural Products- An Insight
title_sort bone health and natural products- an insight
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157411/
https://www.ncbi.nlm.nih.gov/pubmed/30283334
http://dx.doi.org/10.3389/fphar.2018.00981
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