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Partial Mechanical Unloading of the Heart Disrupts L-Type Calcium Channel and Beta-Adrenoceptor Signaling Microdomains

Introduction: We investigated the effect of partial mechanical unloading (PMU) of the heart on the physiology of calcium and beta-adrenoceptor-cAMP (βAR-cAMP) microdomains. Previous studies have investigated PMU using a model of heterotopic-heart and lung transplantation (HTHAL). These studies have...

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Detalles Bibliográficos
Autores principales:	Wright, Peter T., Sanchez-Alonso, Jose L., Lucarelli, Carla, Alvarez-Laviada, Anita, Poulet, Claire E., Bello, Sean O., Faggian, Giuseppe, Terracciano, Cesare M., Gorelik, Julia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157487/ https://www.ncbi.nlm.nih.gov/pubmed/30283354 http://dx.doi.org/10.3389/fphys.2018.01302

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