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Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs
OBJECTIVE: The worldwide prevalence of obesity has increased to 10% in men and 15% in women and is associated with severe comorbidities such as diabetes, cancer, and cardiovascular disease. Animal models of obesity are central to experimental studies of disease mechanisms and therapeutic strategies....
Autores principales: | Renner, Simone, Blutke, Andreas, Dobenecker, Britta, Dhom, Georg, Müller, Timo D., Finan, Brian, Clemmensen, Christoffer, Bernau, Maren, Novak, Istvan, Rathkolb, Birgit, Senf, Steffanie, Zöls, Susanne, Roth, Mirjam, Götz, Anna, Hofmann, Susanna M., Hrabĕ de Angelis, Martin, Wanke, Rüdiger, Kienzle, Ellen, Scholz, Armin M., DiMarchi, Richard, Ritzmann, Mathias, Tschöp, Matthias H., Wolf, Eckhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157610/ https://www.ncbi.nlm.nih.gov/pubmed/30017782 http://dx.doi.org/10.1016/j.molmet.2018.06.015 |
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