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Chronic d-serine supplementation impairs insulin secretion

OBJECTIVE: The metabolic role of d-serine, a non-proteinogenic NMDA receptor co-agonist, is poorly understood. Conversely, inhibition of pancreatic NMDA receptors as well as loss of the d-serine producing enzyme serine racemase have been shown to modulate insulin secretion. Thus, we aim to study the...

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Detalles Bibliográficos
Autores principales:	Suwandhi, Lisa, Hausmann, Simone, Braun, Alexander, Gruber, Tim, Heinzmann, Silke S., Gálvez, Eric J.C., Buck, Achim, Legutko, Beata, Israel, Andreas, Feuchtinger, Annette, Haythorne, Elizabeth, Staiger, Harald, Heni, Martin, Häring, Hans-Ulrich, Schmitt-Kopplin, Philippe, Walch, Axel, Cáceres, Cristina García, Tschöp, Matthias H., Rutter, Guy A., Strowig, Till, Elsner, Martin, Ussar, Siegfried
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157639/ https://www.ncbi.nlm.nih.gov/pubmed/30093356 http://dx.doi.org/10.1016/j.molmet.2018.07.002

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