Cargando…

Prediction and validation of the structural features of Ov58GPCR, an immunogenic determinant of Onchocerca volvulus

Onchocerciasis is a severely debilitating yet neglected tropical disease (NTD) that creates social stigma, generates and perpetuates poverty, and leads ultimately in some cases to irreversible unilateral or bilateral blindness if untreated. Consequently, the disease is a major impediment to socioeco...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shey, Robert Adamu, Ghogomu, Stephen Mbigha, Njume, Ferdinand Ngale, Gainkam, Lea Olive Tchouate, Poelvoorde, Philippe, Mutesa, Leon, Robert, Annie, Humblet, Perrine, Munyampundu, Jean-Pierre, Kamgno, Joseph, Lelubre, Christophe, Vanhamme, Luc, Souopgui, Jacob
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157839/ https://www.ncbi.nlm.nih.gov/pubmed/30256790 http://dx.doi.org/10.1371/journal.pone.0202915

Ejemplares similares

Identification and characterization of the Onchocerca volvulus Excretory Secretory Product Ov28CRP, a putative GM2 activator protein
por: Njume, Ferdinand Ngale, et al.
Publicado: (2019)

The Functional Parasitic Worm Secretome: Mapping the Place of Onchocerca volvulus Excretory Secretory Products
por: Vanhamme, Luc, et al.
Publicado: (2020)

Tandem Use of OvMANE1 and Ov-16 ELISA Tests Increases the Sensitivity for the Diagnosis of Human Onchocerciasis
por: Shintouo, Cabirou Mounchili, et al.
Publicado: (2021)

In Silico Design and Validation of OvMANE1, a Chimeric Antigen for Human Onchocerciasis Diagnosis
por: Shintouo, Cabirou Mounchili, et al.
Publicado: (2020)

In-silico design of a multi-epitope vaccine candidate against onchocerciasis and related filarial diseases
por: Shey, Robert Adamu, et al.
Publicado: (2019)

Immunoinformatics Design and Assessment of a Multiepitope Antigen (OvMCBL02) for Onchocerciasis Diagnosis and Monitoring
por: Yengo, Bernis Neneyoh, et al.
Publicado: (2022)

Nodding syndrome (NS) and Onchocerca Volvulus (OV) in Northern Uganda
por: Lagoro, David Kitara, et al.
Publicado: (2017)

Entomological Assessment of Onchocerca Species Transmission by Black Flies in Selected Communities in the West Region of Cameroon
por: Shintouo, Cabirou Mounchili, et al.
Publicado: (2020)

Onchocerciasis Fingerprints in the Geriatric Population: Does Host Immunity Play a Role?
por: Shintouo, Cabirou Mounchili, et al.
Publicado: (2021)

The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice
por: Hess, Jessica A., et al.
Publicado: (2016)

Barriers to the National Onchocerciasis Control Programme at operational level in Cameroon: a qualitative assessment of stakeholders’ views
por: Dissak-Delon, Fanny Nadia, et al.
Publicado: (2019)

Do Communities Really “Direct” in Community-Directed Interventions? A Qualitative Assessment of Beneficiaries’ Perceptions at 20 Years of Community Directed Treatment with Ivermectin in Cameroon
por: Dissak-Delon, Fanny Nadia, et al.
Publicado: (2019)

Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans
por: George, Parakkal Jovvian, et al.
Publicado: (2019)

Adherence to ivermectin is more associated with perceptions of community directed treatment with ivermectin organization than with onchocerciasis beliefs
por: Dissak-Delon, Fanny Nadia, et al.
Publicado: (2017)

Computational Design and Preliminary Serological Analysis of a Novel Multi-Epitope Vaccine Candidate Against Onchocerciasis and Related Filarial Diseases
por: Shey, Robert Adamu, et al.
Publicado: (2021)

The Onchocerca volvulus Cysteine Proteinase Inhibitor, Ov-CPI-2, Is a Target of Protective Antibody Response That Increases with Age
por: Cho-Ngwa, Fidelis, et al.
Publicado: (2010)

Human immune responses to infective stage larval-specific chitinase of filarial parasite, Onchocerca volvulus, Ov-CHI-1.
por: Wu, Yang, et al.
Publicado: (2003)

Genetic Selection of Low Fertile Onchocerca volvulus by Ivermectin Treatment
por: Bourguinat, Catherine, et al.
Publicado: (2007)

Patent infections with soil-transmitted helminths and Schistosoma mansoni are not associated with increased prevalence of antibodies to the Onchocerca volvulus peptide epitopes OvMP-1 and OvMP-23
por: Vlaminck, Johnny, et al.
Publicado: (2019)

A lipid transfer protein ensures nematode cuticular impermeability
por: Njume, Ferdinand Ngale, et al.
Publicado: (2022)

Molecular and immunological characterization of hr44, a human ocular component immunologically cross-reactive with antigen Ov39 of Onchocerca volvulus
Publicado: (1995)

Performance evaluation of 3 serodiagnostic peptide epitopes and the derived multi-epitope peptide OvNMP-48 for detection of Onchocerca volvulus infection
por: Lagatie, Ole, et al.
Publicado: (2019)

Molecular cloning of an immunodominant antigen of Onchocerca volvulus
Publicado: (1988)

Interruption of Onchocerca volvulus transmission in Northern Venezuela
por: Convit, Jacinto, et al.
Publicado: (2013)

The genome of Onchocerca volvulus, agent of river blindness
por: Cotton, James A., et al.
Publicado: (2016)

Onchocerca volvulus Mimicking Metastatic Breast Carcinoma
por: Nava, Victor E., et al.
Publicado: (2020)

Phenotypic Evidence of Emerging Ivermectin Resistance in Onchocerca volvulus
por: Osei-Atweneboana, Mike Y., et al.
Publicado: (2011)

Elimination of Onchocerca volvulus Transmission in the Huehuetenango Focus of Guatemala
por: Cruz-Ortiz, Nancy, et al.
Publicado: (2012)

The mitogenome of Onchocerca volvulus from the Brazilian Amazonia focus
por: Crainey, James L, et al.
Publicado: (2016)

Neurological manifestations in Onchocerca volvulus infection: A review
por: Hotterbeekx, An, et al.
Publicado: (2019)

Motile Onchocerca volvulus Microfilariae in the Anterior Chamber of the Eye
por: Gyasi, Michael E., et al.
Publicado: (2020)

Pharmacokinetics of oral moxidectin in individuals with Onchocerca volvulus infection
por: Tan, Beesan, et al.
Publicado: (2022)

Multimodal biomarker discovery for active Onchocerca volvulus infection
por: Lagatie, Ole, et al.
Publicado: (2021)

Bacteriome Diversity of Blackflies’ Gut and Association with Onchocerca volvulus, the Causative Agent of Onchocerciasis in Mbam Valley (Center Region, Cameroon)
por: Efon Ekangouo, Arnauld, et al.
Publicado: (2021)

Ivermectin Resistance in Onchocerca volvulus: Toward a Genetic Basis
por: Lustigman, Sara, et al.
Publicado: (2007)

Criteria for the differentiation between young and old Onchocerca volvulus filariae
por: Specht, Sabine, et al.
Publicado: (2009)

Individual exposure to Simulium bites and intensity of Onchocerca volvulus infection
por: Jacobi, C A, et al.
Publicado: (2010)

Newly acquired Onchocerca volvulus filariae after doxycycline treatment
por: Specht, Sabine, et al.
Publicado: (2009)

Interruption of Transmission of Onchocerca volvulus in the Southern Chiapas Focus, México
por: Rodríguez-Pérez, Mario A., et al.
Publicado: (2013)

Comparison of Diagnostic Tests for Onchocerca volvulus in the Democratic Republic of Congo
por: Hotterbeekx, An, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_s0no30ubujq6ianaaapkjkv81b