Cargando…

Theoretical analysis of inducer and operator binding for cyclic-AMP receptor protein mutants

Allosteric transcription factors undergo binding events at inducer binding sites as well as at distinct DNA binding domains, and it is difficult to disentangle the structural and functional consequences of these two classes of interactions. We compare the ability of two statistical mechanical models...

Descripción completa

Detalles Bibliográficos
Autores principales: Einav, Tal, Duque, Julia, Phillips, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157895/
https://www.ncbi.nlm.nih.gov/pubmed/30256816
http://dx.doi.org/10.1371/journal.pone.0204275