Implications of alternative routes to APC/C inhibition by the mitotic checkpoint complex

The mitotic checkpoint (also called spindle assembly checkpoint) is a signaling pathway that ensures faithful chromosome segregation. Mitotic checkpoint proteins inhibit the anaphase-promoting complex (APC/C) and its activator Cdc20 to prevent precocious anaphase. Checkpoint signaling leads to a com...

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Detalles Bibliográficos
Autores principales: Gross, Fridolin, Bonaiuti, Paolo, Hauf, Silke, Ciliberto, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157902/
https://www.ncbi.nlm.nih.gov/pubmed/30199529
http://dx.doi.org/10.1371/journal.pcbi.1006449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157902/
https://www.ncbi.nlm.nih.gov/pubmed/30199529
http://dx.doi.org/10.1371/journal.pcbi.1006449

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