Phenformin and metformin inhibit growth and migration of LN229 glioma cells in vitro and in vivo

BACKGROUND: Malignant glioma is refractory to conventional treatment, highlighting a need to develop novel efficacious therapies. Biguanides, a class of oral antidiabetic drug, have been thought to inhibit proliferation and metastasis in a variety of cancers. PURPOSE: The objective of this study was...

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Detalles Bibliográficos
Autores principales: Wang, Yanmin, Meng, Yanli, Zhang, Shijun, Wu, Huancheng, Yang, Dawei, Nie, Chaohui, Hu, Qunliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157995/
https://www.ncbi.nlm.nih.gov/pubmed/30275708
http://dx.doi.org/10.2147/OTT.S168981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157995/
https://www.ncbi.nlm.nih.gov/pubmed/30275708
http://dx.doi.org/10.2147/OTT.S168981

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