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Phenformin and metformin inhibit growth and migration of LN229 glioma cells in vitro and in vivo

BACKGROUND: Malignant glioma is refractory to conventional treatment, highlighting a need to develop novel efficacious therapies. Biguanides, a class of oral antidiabetic drug, have been thought to inhibit proliferation and metastasis in a variety of cancers. PURPOSE: The objective of this study was...

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Detalles Bibliográficos
Autores principales:	Wang, Yanmin, Meng, Yanli, Zhang, Shijun, Wu, Huancheng, Yang, Dawei, Nie, Chaohui, Hu, Qunliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157995/ https://www.ncbi.nlm.nih.gov/pubmed/30275708 http://dx.doi.org/10.2147/OTT.S168981

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