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The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins
OBJECTIVE: Insulin resistance is associated with impaired receptor dependent hepatic uptake of triglyceride-rich lipoproteins (TRL), promoting hypertriglyceridemia and atherosclerosis. Next to low-density lipoprotein (LDL) receptor (LDLR) and syndecan-1, the LDLR-related protein 1 (LRP1) stimulated...
Autores principales: | Fischer, Alexander W., Albers, Kirstin, Krott, Lucia M., Hoffzimmer, Britta, Heine, Markus, Schmale, Hartwig, Scheja, Ludger, Gordts, Philip L.S.M., Heeren, Joerg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158030/ https://www.ncbi.nlm.nih.gov/pubmed/30100244 http://dx.doi.org/10.1016/j.molmet.2018.07.010 |
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