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HGK-sestrin 2 signaling-mediated autophagy contributes to antitumor efficacy of Tanshinone IIA in human osteosarcoma cells

Tanshinone IIA (TIIA) is a diterpenoid naphthoquinone isolated from the herb Salvia miltiorrhiza with antitumor effects manifested at multiple levels that are mechanistically obscure. In our previous studies, we illustrated that TIIA treatment triggered apoptosis in human osteosarcoma 143B cells bot...

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Detalles Bibliográficos
Autores principales:	Yen, Jia-Hau, Huang, Sheng-Teng, Huang, Hung-Sen, Fong, Yi-Chin, Wu, Yi-Ying, Chiang, Jen-Huai, Su, Yuan-Chih
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158215/ https://www.ncbi.nlm.nih.gov/pubmed/30258193 http://dx.doi.org/10.1038/s41419-018-1016-9

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