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Heterocyclic sterol probes for live monitoring of sterol trafficking and lysosomal storage disorders
The monitoring of intracellular cholesterol homeostasis and trafficking is of great importance because their imbalance leads to many pathologies. Reliable tools for cholesterol detection are in demand. This study presents the design and synthesis of fluorescent probes for cholesterol recognition and...
Autores principales: | Králová, Jarmila, Jurášek, Michal, Krčová, Lucie, Dolenský, Bohumil, Novotný, Ivan, Dušek, Michal, Rottnerová, Zdeňka, Kahle, Michal, Drašar, Pavel, Bartůněk, Petr, Král, Vladimír |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158244/ https://www.ncbi.nlm.nih.gov/pubmed/30258093 http://dx.doi.org/10.1038/s41598-018-32776-6 |
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