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Heterocyclic sterol probes for live monitoring of sterol trafficking and lysosomal storage disorders

The monitoring of intracellular cholesterol homeostasis and trafficking is of great importance because their imbalance leads to many pathologies. Reliable tools for cholesterol detection are in demand. This study presents the design and synthesis of fluorescent probes for cholesterol recognition and...

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Detalles Bibliográficos
Autores principales: Králová, Jarmila, Jurášek, Michal, Krčová, Lucie, Dolenský, Bohumil, Novotný, Ivan, Dušek, Michal, Rottnerová, Zdeňka, Kahle, Michal, Drašar, Pavel, Bartůněk, Petr, Král, Vladimír
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158244/
https://www.ncbi.nlm.nih.gov/pubmed/30258093
http://dx.doi.org/10.1038/s41598-018-32776-6

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