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Loss of the mitochondrial kinase PINK1 does not alter platelet function
PTEN-induced putative kinase (PINK) 1 is regarded as a master regulator of cellular mitophagy such that loss of function mutations contribute to early onset Parkinson’s disease, through aberrant mitochondrial control and function. Mitochondrial function is key to platelet procoagulant activity, cont...
Autores principales: | Walsh, Tony G., van den Bosch, Marion T. J., Lewis, Kirsty E., Williams, Christopher M., Poole, Alastair W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158262/ https://www.ncbi.nlm.nih.gov/pubmed/30258205 http://dx.doi.org/10.1038/s41598-018-32716-4 |
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