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HMGB1 promotes ERK-mediated mitochondrial Drp1 phosphorylation for chemoresistance through RAGE in colorectal cancer

Dysfunctional mitochondria have been shown to enhance cancer cell proliferation, reduce apoptosis, and increase chemoresistance. Chemoresistance develops in nearly all patients with colorectal cancer, leading to a decrease in the therapeutic efficacies of anticancer agents. However, the effect of dy...

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Detalles Bibliográficos
Autores principales:	Huang, Chih-Yang, Chiang, Shu-Fen, Chen, William Tzu-Liang, Ke, Tao-Wei, Chen, Tsung-Wei, You, Ying-Shu, Lin, Chen-Yu, Chao, K. S. Clifford
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158296/ https://www.ncbi.nlm.nih.gov/pubmed/30258050 http://dx.doi.org/10.1038/s41419-018-1019-6

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