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Identification of a novel tRNA wobble uridine modifying activity in the biosynthesis of 5-methoxyuridine

Derivatives of 5-hydroxyuridine (ho(5)U), such as 5-methoxyuridine (mo(5)U) and 5-oxyacetyluridine (cmo(5)U), are ubiquitous modifications of the wobble position of bacterial tRNA that are believed to enhance translational fidelity by the ribosome. In gram-negative bacteria, the last step in the bio...

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Detalles Bibliográficos
Autores principales: Ryu, Huijeong, Grove, Tyler L, Almo, Steven C, Kim, Jungwook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158493/
https://www.ncbi.nlm.nih.gov/pubmed/29982645
http://dx.doi.org/10.1093/nar/gky592

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